Publications

2024

• Morphology and Motility of Cells on Soft Substrates

  Andriy Goychuk David B. Brückner Andrew W. Holle Joachim P. Spatz Chase P. Broedersz Erwin Frey
  submitted for publication.
  [arXiv:1808.00314]

2022

• Geometry adaptation of protrusion and polarity dynamics in confined cell migration

  David B. Brückner Matthew Schmitt Alexandra Fink Johannes Flommersfeld Nicolas Arlt Edouard Hannezo Joachim O. Rädler Chase P. Broedersz
  Physical Review X 12, 031041 (2022).
  [arXiv:2106.01014]

• Exploiting nonlinear elasticity for robust mechanosensation in disordered fiber networks

  Estelle Berthier Pierre Ronceray Chase P. Broedersz
  in preparation.

• Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration

  Themistoklis Zisis* David B. Brückner* Tom Brandstätter Joseph d'Alessandro Angelika Vollmar Chase P. Broedersz Stefan Zahler
  Biophysical Journal 121, 1–17 (2022).
  [biorXiv: 10.1101/2021.05.07.442718]

2021

• Single-cell growth inference of Corynebacterium glutamicum reveals asymptotically linear growth

  Fabian Meyer Marc Bramkamp Chase P. Broedersz
  eLife 10, e70106 (2021).
  [bioRxiv:10.1101/2020.05.25.115055]

• Theory of Active Intracellular Transport by DNA-relaying

  Christian Hanauer Silke Bergeler Erwin Frey Chase P. Broedersz
  Phys. Rev. Lett. 127, 138101 (2021).
  [arXiv:2101.02640]

• Learning the distribution of single-cell chromosome conformations in bacteria reveals emergent order across genomic scales

  Jacqueline Janssen Muriel C.F. van Teeseling Martin Thanbichler Chase P. Broedersz
  Nature Communications 12, 1963 (2021).
  [arXiv:2002.03880]

• Learning the dynamics of cell-cell interactions in confined cell migration

  David B. Brückner Nicolas Arlt Alexandra Fink Pierre Ronceray Joachim O. Rädler Chase P. Broedersz
  PNAS 118 (7), e2016602118 (2021).
  [arXiv:2008.03978]

2020

• Learning the Non-Equilibrium Dynamics of Brownian Movies

  Federico S. Gnesotto Grzegorz Gradziuk Pierre Ronceray Chase P. Broedersz
  Nature Communications 11, 5378 (2020).
  [arXiv:2001.08642]

• Inferring the Dynamics of Underdamped Stochastic Systems

  David B. Brückner Pierre Ronceray Chase P. Broedersz
  Physical Review Letters 125, 058103 (2020),
  featured as Editors' suggestion.
  [arXiv:2002.06680]

• Disentangling the Behavioural Variability of Confined Cell Migration

  David B. Brückner Alexandra Fink Joachim O. Rädler Chase P. Broedersz
  Journal of the Royal Society Interface 17, 20190689 (2020).
  [arXiv:1910.02815] [bioRxiv:10.1101/797555]

• Lattice Kinetic Monte-Carlo Method for Simulating Chromosomal Dynamics and other (Non-)Equilibrium Bio-Assemblies

  Christiaan A. Miermans Chase P. Broedersz
  Soft Matter 16, 544-556 (2020).

2019

• Area and geometry dependence of cell migration in asymmetric two-state micropatterns

  Alexandra Fink David Brückner Christoph Schreiber Peter Röttgermann Chase Broedersz Joachim Rädler
  Biophysical Journal, 118, 552-564 (2019).
  [bioRxiv:10.1101/815472]

• Mesoscopic non-equilibrium measures can reveal intrinsic features of the active driving

  Federica Mura Grzegorz Gradziuk Chase P. Broedersz
  Soft Matter, 15, 8067-8076 (2019).
  [arXiv:1905.13663]

• Non-equilibrium dynamics of isostatic spring networks

  Federico S. Gnesotto Benedikt M. Remlein Chase P. Broedersz
  Physical Review E 100 , 013002 (2019).
  [arXiv:1809.04639]

• Scaling behavior of non-equilibrium measures in internally driven elastic assemblies

  Grzegorz Gradziuk Federica Mura Chase P. Broedersz
  Physical Review E 99, 052406 (2019).
  [arXiv:1901.03132]

• Stochastic nonlinear dynamics of confined cell migration in two-state systems

  David Brückner Alexandra Fink Christoph Schreiber Peter Röttgermann Joachim Rädler Chase Broedersz
  Nature Physics 15, 595–601 (2019).
  [Nature Physics News & Views] [LMU Press Release]

• Fiber plucking by molecular motors yields large emergent contractility in stiff biopolymer networks

  Pierre Ronceray Chase P. Broedersz Martin Lenz
  Soft Matter 15, 1481-1487 (2019).
  [arXiv:1805.04624]

2018

• Stress-dependent amplification of active forces in nonlinear elastic media

  Pierre Ronceray Chase P. Broedersz Martin Lenz
  Soft Matter 15, 331-338 (2019).
  [arXiv:1805.02779]

• Bacterial chromosome organization by collective dynamics of SMC condensins

  Christiaan A. Miermans Chase P. Broedersz
  J. R. Soc. Interface 15, 20180495 (2018).
  [arXiv:1805.03983]

• Non-equilibrium scaling behaviour in driven soft biological assemblies

  Federica Mura Grzegorz Gradziuk Chase P. Broedersz
  Phys. Rev. Lett. 121 (3), 038002 (2018).
  [arXiv:1803.02797]

• Broken detailed balance and non-equilibrium dynamics in living systems

  F. Gnesotto F. Mura J. Gladrow C.P. Broedersz
  Rep. Prog. Phys. 81, 6 (2018).
  [arXiv:1710.03456]

• Guiding 3D cell migration in deformed synthetic hydrogel microstructures

  Miriam Dietrich Hugo Le Roy David B. Brückner Hanna Engelke Roman Zantl Joachim O. Rädler Chase P. Broedersz
  Soft Matter 14, 2816-2826 (2018).

• Looping and clustering model for the organization of partitioning proteins on the bacterial genome

  Jean-Charles Walter Jérôme Dorignac Frédéric Geniet John Palmeri Andrea Parmeggiani Ned S. Wingreen Chase P. Broedersz
  New J. Phys. 20, 035002 (2018).
  [arXiv:1707.01373]

• Cell contraction induces long-ranged stress stiffening in the extracellular matrix

  Yu Long Han Pierre Ronceray Guoqiang Xu Andrea Malandrino Martin Lenz Chase P. Broedersz+ Ming Guo+
  PNAS 115 (16), 4075-4080 (2018).
  [arXiv:1709.00793]

2017

• Nonequilibrium dynamics of probe filaments in actin-myosin networks

  J. Gladrow C.P. Broedersz+ C.F. Schmidt+
  Phys. Rev. E 96, 022408 (2017).
  [arXiv:1704.06243 ]

• Physical limits to biomechanical sensing in disordered fibre networks

  F Beroz LM Jawerth S Münster DA Weitz CP Broedersz+ NS Wingreen+
  Nat. Commun. 8, 16096 (2017).

2016

• Broken Detailed Balance of Filament Dynamics in Active Networks

  J. Gladrow N. Fakhri F.C. MacKintosh C.F. Schmidt C.P. Broedersz
  Phys. Rev. Lett. 116 (24), 248301 (2016).

• Breaking detailed balance at the mesoscale in active biological systems

  C Battle* CP Broedersz* N Fakhri* VF Geyer J Howard CF Schmidt FC MacKintosh
  Science 352, 604-607 (2016).

• Fiber networks amplify active stress

  P Ronceray CP Broedersz+ M Lenz+
  PNAS 113 (11), 2827–2832 (2016).

• Multi-scale strain-stiffening of semiflexible bundle networks

  IK Piechocka KA Jansen CP Broedersz NA Kurniawan FC MacKintosh GH Koenderink
  Soft Matter Advance Article 12 (7), 2145-2156 (2016).

2015

• Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep

  Marina Feric C.P. Broedersz C.P. Brangwynne
  Scientific Reports 5 ,16607 (2015).

• Statistical mechanics of the US Supreme Court

  E.D. Lee C.P. Broedersz W. Bialek
  J. Stat. Phys. 1, 0022-4715 (2015).

2014

• Condensation and localization of the partitioning protein ParB on the bacterial chromosome

  C. P. Broedersz X. Wang Y. Meir J. J. Loparo D. Z. Rudner N. S. Wingreen
  Proc. Natl. Acad. Sci. U.S.A., 111 (24) 8809-8814 (2014).

• Modeling semiflexible polymer networks

  C. P. Broedersz F.C. MacKintosh
  Rev. of Mod. Phys., 86, 995 (2014).

• A New Approach to Analyze Nonlinear Stress Response in Large Amplitude Oscillatory (LAOS) measurement using Parallel Plates

  Z. Fahimi C.P. Broedersz T.H.S. van Kempen D. Florea G.W.M. Peters H.M. Wyss
  Rheologica Acta 53, 75-83 (2014).

2013

• Nuclear mechanics: Lamin webs and pathological blebs

  C.P. Broedersz C.P. Brangwynne
  Nucleus, 4 (3), (2013).

• Dynamical behavior of disordered spring networks

  M.G. Yucht M. Sheinman C.P. Broedersz
  Soft Matter 9, 7000-7006 (2013).

• Stress-enhanced Gelation: A Dynamic Nonlinearity of Elasticity

  N.Y. Yao C.P. Broedersz M. Depken D.J. Becker M.R. Pollak F.C. MacKintosh D.A. Weitz
  Phys. Rev. Lett. 110: 018103 (2013).

• Attenuated short wavelength buckling and force propagation in a biopolymer-reinforced rod

  W.L .Shan Z. Chen C.P. Broedersz A.A. Gumaste W. Soboyejo C.P. Brangwynne
  Soft Matter 9, 194-199 (2013).

2012

• Actively stressed marginal networks

  M. Sheinman C.P. Broedersz F.C. MacKintosh
  Phys. Rev. Lett. 109: 238101 (2012).

• Length-Controlled Elasticity in 3D Fiber Networks

  C.P. Broedersz M. Sheinman F.C. MacKintosh
  Phys. Rev. Lett. 108: 078102 (2012).

• Nonlinear effective medium theory of disordered spring networks

  M. Sheinman C.P. Broedersz F.C. MacKintosh
  Phys. Rev. E, 85, 021801 (2012).

2011

• Criticality and isostaticity in fiber networks

  C.P. Broedersz X. Mao T.C. Lubensky F.C. MacKintosh
  Nature Physics 7, 983-988 (2011).

• Molecular motors stiffen non-affine semiflexible polymer networks

  C.P. Broedersz F.C. MacKintosh
  Soft Matter, 7, 3186-3191 (2011).

• Nonlinear Viscoelasticity of Actin Transiently Cross-linked with Mutant alpha-Actinin-4

  N.Y. Yao D. Becker C.P. Broedersz M. Depken M. Pollak F.C. MacKintosh D.A. Weitz
  Journal of Molecular Biology 411 (5), 1062-1071 (2011).

2010

• Cross-link governed dynamics of biopolymer networks

  C.P. Broedersz M. Depken N.Y. Yao M.R. Pollak D.A. Weitz F.C. MacKintosh
  Phys. Rev. Lett. 105:238101 (2010).

• Nonlinear rheology of cross-linked biopolymer gels

  C.P. Broedersz K.E. Kasza L.M. Jawerth S. Muenster D.A. Weitz F.C. MacKintosh
  Soft Matter 6, 4120 (2010).

• Divalent Cations Crosslink Vimentin Intermediate Filament Tail Domains to Regulate Network Mechanics

  Y.C. Lin C.P. Broedersz A.C. Rowat T. Wedig H. Herrmann F.C. MacKintosh D.A. Weitz
  Journal of Molecular Biology 399, 637-644 (2010).

• Elasticity in ionically cross-linked neurofilament networks

  N.Y. Yao C.P. Broedersz Y.C. Lin K.E. Kasza F.C. MacKintosh D.A. Weitz
  Biophysical Journal 98, 2147-2153 (2010).

• Origins of elasticity in intermediate filament networks

  Y.C. Lin N.Y. Yao C.P. Broedersz H. Herrmann F.C. MacKintosh D.A. Weitz
  Phys. Rev. Lett., 104:058101 (2010).

• Actin filament length tunes elasticity of flexibly crosslinked actin networks

  K.E. Kasza C.P. Broedersz G.H. Koenderink Y.C. Lin W. Messner E.A. Millman F. Nakamura T.P. Stossel F.C. MacKintosh D.A. Weitz
  Biophysical Journal 99, 1091 (2010).

2009

• Hydrogenography of MgyNi1-yHx gradient thin films: Interplay between the thermodynamics and kinetics of hydrogenation

  R. Gremaud C.P. Broedersz A. Borgschulte M.J. van Setten H. Schreuders M. Slaman B. Dam R. Griessen
  Acta Mater. 58, 658-668 (2009).

• Effective medium approach for stiff polymer networks with flexible cross-links

  C.P. Broedersz C. Storm F.C. MacKintosh
  Phys. Rev. E 79, 061914 (2009).

• Nonlinear elasticity of stiff biopolymers connected by flexible linkers

  K.E. Kasza G.H. Koenderink Y.C. Lin C.P. Broedersz W. Messner F. Nakamura T.P. Stossel F.C. MacKintosh D.A. Weitz
  Phys. Rev. E 79, 041928 (2009).

2008

• Nonlinear elasticity of composite networks of stiff biopolymers with flexible linkers

  C.P. Broedersz C. Storm F. C. MacKintosh
  Phys. Rev. Lett. 101:118103 (2008).

• The highly destabilized Mg-Ti-Ni-H system investigated by density functional calculations and hydrogenography experiments

  C.P. Broedersz R. Gremaud B. Dam R. Griessen O.M. Lovvik
  Phys. Rev. B 77, 024204 (2008).

• Tuning the electrical, structural and optical properties of in-situ grown MgH2 thin films by activated reactive evaporation

  R.J. Westerwaal C.P. Broedersz R. Gremaud M. Slaman A. Borgschulte W. Lohstroh K.G. Tschersich H.P. Fleischhauer B. Dam R. Griessen
  Thin Solid Films 516, 4351-4359 (2008).

2007

• Highly destabilized Mg-based hydrogen storage materials identified through combinatorial screening

  R. Gremaud C.P. Broedersz D. Borsa A. Borgschulte P. Mauron H. Schreuders J.H. Rector B. Dam R. Griessen
  Advanced Materials 19, 2813 - 2817 (2007).

• Combinatorial thin film methods for the search of new light-weight metal-hydrides

  B. Dam R. Gremaud C. Broedersz R. Griessen
  Scripta Materialia 56, 853-858 (2007).

2006

• Optical, structural, and electrical properties of Mg2NiH4 thin films in-situ grown by activated reactive evaporation

  R.J. Westerwaal M. Slaman A. Borgschulte C.P. Broedersz D.M. Borsa W. Lohstroh B. Kooi G. ten Brink K.G. Tschersich H.P. Fleischhauer B. Dam R. Griessen
  Journal of Applied Physics 100, 063518 (2006).