Statistical and Biological Physics

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Control of protein-based pattern formation via guiding cues

Tom Burkart*, Manon C. Wigbers*, Laeschkir Würthner* and Erwin Frey

guiding_cues Picture by Craiyon

Proteins control many vital functions in living cells, such as cell growth and cell division. Reliable coordination of these functions requires spatial and temporal organizaton of proteins inside cells, which encodes information about the cell geometry and the current state in the cell cycle. Here, we review how protein patterns are guided by the cell size and shape, by other protein patterns that act as template, and by the mechanical properties of the cell. We posit that understanding the controlled formation of protein patterns in cells will be an essential part of understanding information processing in living systems.



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