Fields of Research
My current research focuses on pattern formation in biological systems. I apply the tools of theoretical biophysics, statistical physics, and nonlinear dynamics to reveal the mechanisms underlying various pattern-forming instabilities. Examples include protein patterns in heterogeneous systems, geometry-induced patterns, and morphological instabilities of growing protein-lipid interfaces.
Contact
D-80333 Munich
Room:
A339
Phone:
+49 (0)89 2180-4560
Email:
L.Wuerthner@physik.uni-muenchen.de
Research Interests
- Protein-based pattern formation
- Coarse-graining and multiscale systems
- Kinetic roughening of protein-lipid interfaces
- Pattern prediction based on neural networks
Curriculum Vita
- 2016-2022: Ph.D. student in the group of Prof. Dr. Erwin Frey
- 2014-2016: Master studies of Physics, LMU Munich
- 2013-2014: Bachelor studies of Physics, LMU Munich
- 2009-2013: Bachelor studies of Engineering Physics, University of Applied Sciences Munich
- 2008-2009: Technical diploma, Munich, Germany
- 2005-2008: Vocational training in IT-Systems Engineering, Munich, Germany
Publications
2023
-
Self-organising protein-lipid nanodomains (PLDs) enable cell-like membrane reshaping and scission
A.B. Petrova T. Burkart A.F. Montanarella D. Sazcko-Brack L. Würthner A. Graw E. Frey C. Veigelsubmitted for publication. -
Robust and resource-optimal dynamic pattern formation of Min proteins in vivo
Ziyuan Ren* Henrik Weyer* Laeschkir Würthner Dongyang Li Cindy Sou Daniel Villarreal Erwin Frey+ Suckjoon Jun+submitted for publication.[bioRxiv:2023.08.15.553443] -
Geometry-induced patterns through mechanochemical coupling
Laeschkir Würthner* Andriy Goychuk* Erwin Frey [arXiv:2205.02820]
2022
-
Bridging scales in a multiscale pattern-forming system
Laeschkir Würthner* Fridtjof Brauns* Grzegorz Pawlik Jacob Halatek Jacob Kerssemakers Cees Dekker Erwin Frey [arXiv:2111.12043] -
Control of protein-based pattern formation via guiding cues
Tom Burkart* Manon C. Wigbers* Laeschkir Würthner* Erwin Frey [bioRxiv: 10.1101/2022.02.11.480095] -
Control of protein-based pattern formation via guiding cues
Tom Burkart* Manon C. Wigbers* Laeschkir Würthner* Erwin Frey [bioRxiv: 10.1101/2022.02.11.480095]
2021
-
Dynamics of the Bacillus subtilis Min system
Helge Feddersen Laeschkir Würthner Erwin Frey Marc Bramkamp [bioRxiv:10.1101/2020.04.29.068676]
2020
-
Geometric cues stabilise long-axis polarisation of PAR protein patterns in C. elegans
Raphaela Geßele Jacob Halatek Laeschkir Würthner Erwin Frey [bioRxiv:10.1101/451880]