Projects and Research Interests
Broadly interested in applying the methods and tools of theoretical biophysics, statistical mechanics and nonlinear dynamics to biological phenomena involving (among others): biomechanics and biochemistry; cell, tissue and population growth; cell migration; and population dynamics. The projects that I work on include:
- Single and collective cell migration in soft and rigid environments
- Computer vision and machine learning for cell detection
- Mass conserving reaction-diffusion systems in deforming geometries
- Mechanochemical interactions on the microscale
- Angiogenesis
Curriculum Vitae
- Since 2016: PhD Student in Physics at the LMU
- 2013—2016: Master Studies in Physics at the LMU. Master Thesis: “Tube Formation of Endothelial Cells — Quantitative analysis of two-dimensional tube formation assays and their numerical simulation on a cell level”
- 2010—2013: Bachelor Studies in Physics at the LMU. Bachelor Thesis: “Angiogenesis and Vasculogenesis — Development of a Mathematica-toolset for the analysis of experimental videos”
- 2010: General qualification for university entrance (Abitur). Holbein Gymnasium, Augsburg, Germany
Publications
2024
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Self-consistent sharp interface theory of active condensate dynamics
Andriy Goychuk Leonardo Demarchi Ivan Maryshev Erwin Freysubmitted for publication.[arXiv:2401.17111] -
Tissue flow through pores: a computational study
Felix Kempf Andriy Goychuk Erwin Freysubmitted for publication.[bioRxiv: 10.1101/2021.03.25.436985] -
Morphology and Motility of Cells on Soft Substrates
Andriy Goychuk David B. Brückner Andrew W. Holle Joachim P. Spatz Chase P. Broedersz Erwin Freysubmitted for publication.[arXiv:1808.00314]
2023
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Geometry-induced patterns through mechanochemical coupling
Laeschkir Würthner* Andriy Goychuk* Erwin Frey [arXiv:2205.02820] -
Enzyme-enriched condensates show self-propulsion, positioning, and coexistence
Leonardo Demarchi Andriy Goychuk Ivan Maryshev Erwin Frey [Droplets Come to Life (Viewpoint Article by David Zwicker, Physics 16, 45)] [arXiv:2301.00392]
2021
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Surface tension induced budding drives alveologenesis in human mammary gland organoids
Pablo A. Fernández* Benedikt Buchmann* Andriy Goychuk* Lisa Engelbrecht Marion Raich Christina Scheel Erwin Frey+ Andreas R. Bausch+ -
A diffusiophoretic mechanism for ATP-driven transport without motor proteins
Beatrice Ramm* Andriy Goychuk* Alena Khmelinskaia Philipp Blumhardt Kristina Ganzinger Erwin Frey+ Petra Schwille+ [bioRxiv:10.1101/2020.05.01.072744] -
Optically Transparent Vertical Silicon Nanowire Arrays for Live-Cell Imaging
A. Kosloff A. W. Holle J. Young M. A. George O. Heifler A. Goychuk E. Frey J. P. Spatz F. Patolsky R. Elnathan N. H. Voelcker
2020
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Cell-Based Strain Remodeling of a Nonfibrous Matrix as an Organizing Principle for Vasculogenesis
Daniel Rüdiger Kerstin Kick Andriy Goychuk Angelika M. Vollmar Erwin Frey Stefan Zahler [bioRxiv:10.1101/816496] -
Quasi-periodic migration of single cells on short microlanes
Fang Zhou Sophia A. Schaffer Christoph Schreiber Felix J. Segerer Andriy Goychuk Erwin Frey Joachim O. Rädler [bioRxiv:10.1101/809939]
2019
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Bridging the gap between single cell migration and collective dynamics
Florian Thüroff* Andriy Goychuk* Matthias Reiter Erwin Frey [bioRxiv:10.1101/548677] -
Protein recruitment through indirect mechanochemical interactions
Andriy Goychuk Erwin Frey [arXiv:1910.00977]